منابع مشابه
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.
Strategies to treat cancer have focused primarily on the killing of tumor cells. Here, we describe a differential stress resistance (DSR) method that focuses instead on protecting the organism but not cancer cells against chemotherapy. Short-term starved S. cerevisiae or cells lacking proto-oncogene homologs were up to 1,000 times better protected against oxidative stress or chemotherapy drugs ...
متن کاملExtraordinary starvation resistance in
Ant colony mortality has not been sufficiently studied, even though it is crucial for understanding social insect population biology and can serve as an important model for general aging and mortality processes. Particularly, studies on proximate mechanisms on mortality and stress resistance of ant colonies are lacking. This study explores the long-term colony starvation resistance of the small...
متن کاملCarbon-Starvation Induces Cross-Resistance to Thermal, Acid, and Oxidative Stress in Serratia marcescens
The broad host-range pathogen Serratia marcescens survives in diverse host and non-host environments, often enduring conditions in which the concentration of essential nutrients is growth-limiting. In such environments, carbon and energy source starvation (carbon-starvation) is one of the most common forms of stress encountered by S. marcescens. Related members of the family Enterobacteriaceae ...
متن کاملTransgenerational effects of early life starvation on growth, reproduction and stress resistance in C. elegans
Starvation during early development can have lasting effects that influence organismal fitness and disease risk. We characterized the long-term phenotypic consequences of starvation during early larval development in Caenorhabditis elegans to determine potential fitness effects and develop it as a model for mechanistic studies. We varied the amount of time that larvae were developmentally arres...
متن کاملTransgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in Caenorhabditis elegans.
Starvation during early development can have lasting effects that influence organismal fitness and disease risk. We characterized the long-term phenotypic consequences of starvation during early larval development in Caenorhabditis elegans to determine potential fitness effects and develop it as a model for mechanistic studies. We varied the amount of time that larvae were developmentally arres...
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ژورنال
عنوان ژورنال: Trends in Endocrinology & Metabolism
سال: 2018
ISSN: 1043-2760
DOI: 10.1016/j.tem.2018.01.008